Organic optoelectronics for lab-on-chip fluorescence detection

Improving fluorescence detection in lab on chip devices.

A High-sensitivity On-chip Fluorescence Detection for Lab-on-a-chip

In this paper, we present an improved high-sensitivity approach for on-chip fluorescence-based measurements for disposable lab-on-a-chip (LOC). We use a bilayer organic photodiode (OPD), cross-polarization, and improved integration to enhance Rhodamine 6G limit of detection (LOD) to 10 nM, which is a 10-100 fold improvement over current reports in literature. A prototype system was fully charac...

Plastic lab-on-a-chip for fluorescence excitation with integrated organic semiconductor lasers.

Laser light excitation of fluorescent markers offers highly sensitive and specific analysis for bio-medical or chemical analysis. To profit from these advantages for applications in the field or at the point-of-care, a plastic lab-on-a-chip with integrated organic semiconductor lasers is presented here. First order distributed feedback lasers based on the organic semiconductor tris(8-hydroxyqui...

An integrated hybrid interference and absorption filter for fluorescence detection in lab-on-a-chip devices.

We present a hybrid optical filter design that combines interference and absorbing components for enhanced fluorescence detection in miniaturized highly-integrated lab-on-a-chip devices. The filter is designed in such a way that the advantages of each technology are used to offset the disadvantages of the other. The filter is fabricated with microfabrication compatible processes and materials f...

An integrated fluorescence detection system for lab-on-a-chip applications.

We present a low-cost miniaturized fluorescence detection system for lab-on-a-chip applications with a sensitivity in the low nanomolar range; a built-in lock-in amplifier enables measurements under ambient light.